Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963531 | 1.00 | ELANE (0.44) | ELANEMEN1KMT2AKIF11TSHR | |
| SCHEMBL5963538 | 0.77 | ELANE (0.51) | ELANEMEN1KMT2AKIF11TSHR | |
| SCHEMBL5963957 | 0.77 | RIPK1 (0.49) | ELANEMEN1KMT2AKIF11TSHR | |
| SCHEMBL8487905 | 0.77 | KMT2A (0.43) | ELANEMEN1KMT2AP2RX4RIPK1 | |
| SCHEMBL9407814 | 0.77 | KMT2A (0.43) | ELANEMEN1KMT2AP2RX4RIPK1 | |
| SCHEMBL9344671 | 0.77 | KMT2A (0.43) | ELANEMEN1KMT2AP2RX4RIPK1 | |
| SCHEMBL5964257 | 0.75 | KDM4E (0.48) | ELANEMEN1KMT2ATSHRPOLB | |
| SCHEMBL5963755 | 0.75 | ELANE (0.42) | ELANESMN1; SMN2P2RX4BCHECYP2C9 | |
| SCHEMBL5963534 | 0.74 | ELANE (0.44) | ELANEBCHERIPK1 | |
| SCHEMBL16237822 | 0.74 | ELANE (0.44) | ELANEBCHERIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187916-B1 | Process for the preparation of taxane derivatives and β-lactam intermediates therefor | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-02-13 | — | — | US | disclosed |