Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.41 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964586 | 0.92 | FAAH (0.45) | ADRB3ADRB1FAAHADRB2CNR2 | |
| SCHEMBL5964196 | 0.85 | FAAH (0.42) | ADRB1FAAHADRB2CNR2ALOX5AP | |
| SCHEMBL5964318 | 0.78 | CNR2 (0.60) | CNR2ALOX5APFEN1 | |
| SCHEMBL5964374 | 0.78 | ADRB1 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5964497 | 0.77 | MEN1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6195433 | 0.73 | CNR2 (0.47) | ADRB3ADRB1FAAHADRB2CNR2 | |
| SCHEMBL5964717 | 0.72 | PKM (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5964271 | 0.71 | ADRB3 (0.53) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6767270 | 0.71 | KMT2A (0.59) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5964144 | 0.69 | ADRB3 (0.56) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052315-A1 | Cb 1/cb 2 receptor ligands and their use in the treatment of pain | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | US | claimed |
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052315-A1 | Cb 1/cb 2 receptor ligands and their use in the treatment of pain | CNR1, CNR2, OPRL1 | ADRB3 86/4885ADRB1 23/4885FAAH 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.