Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.52 |
| ▸ | THRB | P10828 | 11/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | CDC42 | P60953 | 1/20 | 0.41 |
| ▸ | RAC1 | P63000 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964865 | 0.85 | TTR (0.48) | PTGS1PTGS2AKR1C3AKR1C2CDC42 | |
| SCHEMBL5964846 | 0.84 | THRA (0.48) | THRATHRBPTGS1PTGS2AKR1C3 | |
| SCHEMBL5858288 | 0.84 | PTGS2 (0.54) | THRATHRBPTGS1PTGS2AKR1C3 | |
| SCHEMBL5964537 | 0.83 | THRA (0.62) | THRATHRB | |
| SCHEMBL5964844 | 0.81 | THRA (0.58) | THRATHRB | |
| SCHEMBL5964560 | 0.81 | THRA (0.44) | THRATHRBPPARGPTGS1 | |
| SCHEMBL5964592 | 0.79 | THRA (0.53) | THRATHRB | |
| SCHEMBL5964843 | 0.78 | THRA (0.73) | THRATHRB | |
| SCHEMBL5861511 | 0.78 | THRB (0.52) | THRATHRBPPARGCYP1A2TSHR | |
| SCHEMBL5964528 | 0.78 | THRA (0.49) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153997-B2 | Benzamide derivatives as thyroid receptor ligands | KARO BIO AB (SE) | 2006-12-26 | — | — | US | disclosed |
| US-20060135614-A1 | Novel compounds | NORIN, THOMAS ANDERS WILSON (SE) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135614-A1 | Novel compounds | THRB, TSHR, THRA | THRA 3/4885THRB 1/4885PPARG 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.