SCHEMBL596455

SCHEMBL596455

[O]C(=O)c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11809728 0.83
SCHEMBL211487 0.82 CES2 (1.00)
SCHEMBL29466797 0.82 CES2 (1.00)
SCHEMBL31369148 0.82 KMT2A (0.75)
SCHEMBL87791 0.82 KMT2A (0.75)
SCHEMBL29466796 0.82 CES2 (1.00)
2-Picolinic Acid SCHEMBL674850 0.81 CES2 (0.64)
SCHEMBL11084150 0.80
Water SCHEMBL6228901 0.80 KMT2A (0.72)
2-Picolinic Acid SCHEMBL7457912 0.80 LMNA (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112512529-B Cyclopentenepurine derivative or salt thereof 富士胶片株式会社 2024-06-18 CN claimed
CN-117440961-A Nucleoside medicine for treating or preventing coronavirus infection and application thereof 北京沐华生物科技有限责任公司 2024-01-23 CN claimed
CN-116987118-A Nucleoside medicine for treating or preventing coronavirus infection and application thereof 北京沐华生物科技有限责任公司 2023-11-03 CN claimed
WO-2023208108-A1 COMPOUND FOR REDUCING URIC ACID 江苏新元素医药科技有限公司 2023-11-02 WO claimed
WO-2023208103-A1 COMPOUND CAPABLE OF BEING USED FOR GOUT 江苏新元素医药科技有限公司 2023-11-02 WO claimed
CN-116715633-A Compounds useful for uric acid reduction 江苏新元素医药科技有限公司 2023-09-08 CN claimed
US-20200390100-A1 SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2020-12-17 US claimed
EP-3728214-A1 SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2020-10-28 EP claimed
CN-111727185-A Substituted N-heterocyclyl-and N-heteroaryltetrahydropyrimidines and their salts and their use as herbicidal active substances 拜耳公司 2020-09-29 CN claimed
US-20200079765-A1 SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2020-03-12 US claimed
EP-0252005-A1 Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds CIBA-GEIGY AG (CH) 1988-01-07 EP claimed
US-4604397-A Certain benzo-(pyrano and thiopyrano)-pyridines, useful as CNS agents CIBA-GEIGY CORPORATION (US) 1986-08-05 US claimed
EP-0161218-A2 Benzo-(pyrano and thiopyrano)pyridines CIBA-GEIGY AG (CH) 1985-11-13 EP claimed
EP-0058779-B1 CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES Dr. Karl Thomae GmbH (DE) 1984-09-19 EP claimed
EP-0061425-A2 Thiazole derivatives, processes for their preparation, medicaments containing them and their use CIBA-GEIGY AG (CH) 1982-09-29 EP claimed
EP-0058779-A2 Carboxamides, their preparation and their use as medicines Dr. Karl Thomae GmbH (DE) 1982-09-01 EP claimed
US-4119777-A BY OXIDATION OF A THIOAMIDE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1978-10-10 US claimed
US-4000144-A HYPOLIPIDAEMIC AGENTS AND ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1976-12-28 US claimed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US claimed
US-3933835-A ANTIALLERGENS, HYPOLIPIDAEMIC CIBA-GEIGY CORPORATION (US) 1976-01-20 US claimed