Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | KYNU | Q16719 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646832 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15KYNUSIRT2SIRT1 | |
| SCHEMBL10054772 | 0.94 | ALDH1A1 (0.56) | ALDH1A1ALOX15KYNUCTSKCTSL | |
| SCHEMBL6259518 | 0.90 | KYNU (0.60) | ALDH1A1ALOX15KYNUSIRT2SIRT1 | |
| SCHEMBL221391 | 0.90 | KYNU (0.60) | ALDH1A1ALOX15KYNUSIRT2SIRT1 | |
| SCHEMBL2777678 | 0.90 | KYNU (0.60) | ALDH1A1ALOX15KYNUSIRT2SIRT1 | |
| SCHEMBL27626645 | 0.90 | FOLH1 (0.57) | ALDH1A1ALOX15SIRT2SIRT1CTSK | |
| SCHEMBL116479 | 0.90 | FOLH1 (0.57) | ALDH1A1ALOX15SIRT2SIRT1CTSK | |
| SCHEMBL11053442 | 0.89 | KYNU (0.59) | ALDH1A1ALOX15KYNUSIRT2SIRT1 | |
| SCHEMBL7087075 | 0.89 | KYNU (0.59) | ALDH1A1ALOX15KYNUSIRT2SIRT1 | |
| SCHEMBL8224981 | 0.89 | KYNU (0.59) | ALDH1A1ALOX15KYNUSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229254-A1 | Compounds having prolyl oligopeptidase inhibitory activity | ORION CORPORATION (FI) | 2006-10-12 | — | — | US | disclosed |
| EP-1581489-A2 | COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY | ORION CORPORATION (FI) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004060862-A2 | COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY | ORION CORPORATION (FI) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229254-A1 | Compounds having prolyl oligopeptidase inhibitory activity | PREP, DNPEP, IDE | ALDH1A1 2051/4885ALOX15 2741/4885KYNU 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.