Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967612 | 0.90 | KDM4E (0.45) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL5967630 | 0.88 | ACE (0.39) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL5967595 | 0.86 | ZDHHC7 (0.32) | ZDHHC7POLBGFERMEN1KMT2A | |
| SCHEMBL6290868 | 0.84 | ACE (0.36) | ACE | |
| SCHEMBL5967572 | 0.82 | MME (0.33) | ACEZDHHC7 | |
| SCHEMBL5967597 | 0.79 | TLR2 (0.32) | ZDHHC7 | |
| SCHEMBL5967600 | 0.79 | GPR139 (0.42) | ACERECQLSMN1; SMN2FNTAFNTB | |
| SCHEMBL5967623 | 0.76 | — | — | |
| SCHEMBL5967587 | 0.76 | SIRT6 (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1487648 | 0.75 | KDM4E (0.49) | ACEKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989372-B1 | Antioxidants, preparation methods and uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-01-24 | — | — | US | disclosed |
| US-6979747-B2 | Antioxidants, preparation processes and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-12-27 | — | — | US | disclosed |