SCHEMBL5969147

SCHEMBL5969147

C=C(CCCCOS(=O)(=O)O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.46
FNTB P49356 2/20 0.46
CA1 P00915 8/20 0.35
CA2 P00918 8/20 0.35
CA9 Q16790 8/20 0.35
CA12 O43570 2/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA7 P43166 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5969166 0.94 FNTA (0.40) FNTAFNTBCA1CA2CA9
SCHEMBL5969124 0.86 FNTA (0.35) FNTAFNTB
SCHEMBL8717347 0.83 FNTA (0.56) FNTAFNTBCA1CA2CA9
SCHEMBL15845914 0.77 TP53 (0.33) CA1CA2CA9CA12CA3
SCHEMBL1706206 0.77 FNTA (0.49) FNTAFNTB
SCHEMBL10901940 0.77 TDP1 (0.40) ALDH1A1LMNAALOX15TSHR
SCHEMBL17672227 0.75 LMNA (0.38) ALDH1A1LMNAALOX15TSHR
SCHEMBL435733 0.75 LMNA (0.38) ALDH1A1LMNAALOX15TSHR
SCHEMBL1858134 0.75 LMNA (0.38) ALDH1A1LMNAALOX15TSHR
SCHEMBL730324 0.75 LMNA (0.38) ALDH1A1LMNAALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6406687-B1 POLYOXYALKYLENE ETHER, SULFATE, SULFONATE AND SULFAMATE AS ANTICOAGULANTS BIOINTERACTIONS LTD. (GB) 2002-06-18 US claimed
US-6096798-A COATING MATERIALS FOR MEDICAL DEVICES, SUCH AS TUBING OR CONNECTORS BIOINTERACTIONS LTD. (GB) 2000-08-01 US claimed
EP-0896600-B1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS LUTHRA AJAY KUMAR (GB) 2000-01-12 EP claimed
EP-0896600-A1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS Luthra, Ajay Kumar (GB) 1999-02-17 EP claimed
WO-1997041164-A1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS LUTHRA AJAY KUMAR (GB) 1997-11-06 WO claimed
US-RE49528-E1 Bioactive coatings BIOINTERACTIONS LTD. (GB) 2023-05-16 US disclosed
US-RE49522-E1 Bioactive coatings BIOINTERACTIONS LTD. (GB) 2023-05-09 US disclosed
CN-114957564-A Bioactive coating 生物相互作用有限公司 2022-08-30 CN disclosed
EP-3699220-A1 BIOACTIVE COATINGS Biointeractions Ltd (GB) 2020-08-26 EP disclosed
CN-110776610-A Bioactive coating 生物相互作用有限公司 2020-02-11 CN disclosed
CN-105517585-B Bioactivity coatings 生物相互作用有限公司 2019-11-22 CN disclosed
US-10206945-B2 Bioactive coatings BIOINTERACTIONS LTD. (GB) 2019-02-19 US disclosed
US-20140322287-A1 BIOACTIVE COATINGS BIOINTERACTIONS LTD. (GB) 2014-10-30 US disclosed
WO-2014174237-A1 BIOACTIVE COATINGS BIOINTERACTIONS LIMITED (GB) 2014-10-30 WO disclosed
US-7034061-B1 Non-thrombogenic and anti-thrombogenic polymers BIOINTERACTIONS LTD. (GB) 2006-04-25 US disclosed
US-6406687-B1 POLYOXYALKYLENE ETHER, SULFATE, SULFONATE AND SULFAMATE AS ANTICOAGULANTS BIOINTERACTIONS LTD. (GB) 2002-06-18 US disclosed
US-6096798-A COATING MATERIALS FOR MEDICAL DEVICES, SUCH AS TUBING OR CONNECTORS BIOINTERACTIONS LTD. (GB) 2000-08-01 US disclosed
EP-0896600-B1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS LUTHRA AJAY KUMAR (GB) 2000-01-12 EP disclosed
EP-0896600-A1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS Luthra, Ajay Kumar (GB) 1999-02-17 EP disclosed
WO-1997041164-A1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS LUTHRA AJAY KUMAR (GB) 1997-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140322287-A1 BIOACTIVE COATINGS SERPINC1, PLAT, FGB FNTA 1407/4885FNTB 2133/4885CA1 3240/4885
US-10206945-B2 Bioactive coatings SERPINC1, PLAT, FGB FNTA 1407/4885FNTB 2133/4885CA1 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.