Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640045 | 0.96 | HTT (0.63) | HTTSMN1; SMN2CTBP2CA1CA2 | |
| SCHEMBL14813139 | 0.84 | HTT (0.59) | HTTSMN1; SMN2CTBP2CA1CA2 | |
| SCHEMBL3628705 | 0.83 | HTT (0.68) | HTTSMN1; SMN2CTBP2LDHAALDH1A1 | |
| SCHEMBL5791802 | 0.82 | CTBP2 (0.64) | HTTSMN1; SMN2CTBP2LDHAALDH1A1 | |
| SCHEMBL48525 | 0.81 | HTT (0.66) | HTTSMN1; SMN2CTBP2LDHAALDH1A1 | |
| SCHEMBL28709451 | 0.81 | HTT (0.66) | HTTSMN1; SMN2CTBP2LDHAALDH1A1 | |
| SCHEMBL240822 | 0.81 | KDM4E (0.74) | HTTSMN1; SMN2CTBP2CA2LDHA | |
| SCHEMBL1525068 | 0.81 | HTT (0.66) | HTTSMN1; SMN2CTBP2LDHAALDH1A1 | |
| SCHEMBL4643470 | 0.80 | HTT (0.59) | HTTSMN1; SMN2CTBP2LDHAALDH1A1 | |
| SCHEMBL7642020 | 0.80 | HTT (0.65) | HTTSMN1; SMN2CTBP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | PGLS, ABCG2, UGCG | HTT 4764/4885SMN1; SMN2 4826/4885CTBP2 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.