Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5970151 | 0.85 | CPA1 (0.46) | CPA1CPA2CPA4PLGSIRT5 | |
| SCHEMBL5970337 | 0.83 | HDAC4 (0.44) | SIRT5HDAC1HDAC4SIRT1HDAC3 | |
| SCHEMBL5970275 | 0.80 | SIRT5 (0.54) | SIRT5CA1CA2HDAC1HDAC4 | |
| SCHEMBL5970128 | 0.80 | SIRT5 (0.44) | CPA1CPA2CPA4PLGSIRT5 | |
| SCHEMBL5970177 | 0.79 | PLG (0.48) | CPA1CPA2CPA4PLGSIRT5 | |
| SCHEMBL5970389 | 0.78 | CPA1 (0.43) | CPA1CPA2CPA4PLGSIRT5 | |
| SCHEMBL5970592 | 0.78 | SIRT5 (0.54) | CPA1CPA2CPA4SIRT5CA1 | |
| SCHEMBL5970299 | 0.78 | FNTA (0.46) | CPA1CPA2CPA4SIRT5HDAC1 | |
| SCHEMBL5970296 | 0.78 | CPA1 (0.43) | CPA1CPA2CPA4PLGSIRT5 | |
| SCHEMBL5970328 | 0.78 | ALDH1A1 (0.47) | CPA1CPA2CPA4PLGSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080070-B1 | ANTIANGIOGENIC DRUG TO TREAT CANCER, ARTHRITIS AND RETINOPATHY | ABBOTT LAB (US) | 2006-11-22 | — | — | EP | claimed |