Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 3/20 | 0.43 |
| ▸ | P4HB | P07237 | 8/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5970509 | 0.91 | PDCD1 (0.54) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL6795707 | 0.77 | PDCD1 (0.49) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL8153247 | 0.77 | PDCD1 (0.50) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL5970508 | 0.77 | PDCD1 (0.49) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL5970912 | 0.75 | PDCD1 (0.51) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL6981746 | 0.75 | AKR1C3 (0.59) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL3115027 | 0.75 | AKR1C3 (0.59) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL28372992 | 0.75 | AKR1C3 (0.59) | PDCD1CD274FBP1P4HBGSK3B | |
| SCHEMBL5971061 | 0.75 | PDCD1 (0.62) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL5971058 | 0.75 | PDCD1 (0.62) | PDCD1CD274FBP1P4HBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245564-B1 | BENZAMIDINE DERIVATIVES | SANKYO CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-20040248981-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-12-09 | — | — | US | disclosed |
| US-20040010009-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-01-15 | — | — | US | disclosed |
| US-6555556-B1 | N-(4-(1-acetimidoylpiperidin-4-yl)oxyphenyl)-N-((E)-3-(3 -amidinophenyl)-2-methyl-2-propenyl)sulfamoylacetic acid dihydrochloride for example; factor Xa inhibitors | SANKYO COMPANY, LIMITED (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010009-A1 | Benzamidine derivatives | HABP2, F7, F2 | PDCD1 3406/4885CD274 4342/4885FBP1 594/4885 |
| US-20040248981-A1 | Benzamidine derivatives | HABP2, F7, F2 | PDCD1 3414/4885CD274 4296/4885FBP1 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.