Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150918 | 0.94 | PDCD1 (0.51) | PDCD1CD274POLBAPEX1HTT | |
| SCHEMBL8143850 | 0.90 | POLB (0.40) | PDCD1CD274POLBAPEX1HTT | |
| SCHEMBL8157213 | 0.88 | POLB (0.43) | PDCD1CD274POLBAPEX1HTT | |
| SCHEMBL8144621 | 0.85 | DNM1 (0.39) | PDCD1CD274POLBAPEX1HTT | |
| SCHEMBL8156645 | 0.84 | PTGS2 (0.43) | POLBAPEX1HTTTDP1FBP1 | |
| SCHEMBL8152091 | 0.83 | APEX1 (0.36) | PDCD1CD274POLBAPEX1HTT | |
| SCHEMBL8157860 | 0.81 | GLO1 (0.52) | FBP1KDM4EMAPT | |
| SCHEMBL8152013 | 0.81 | FBP1 (0.40) | PDCD1CD274POLBAPEX1HTT | |
| SCHEMBL8547870 | 0.79 | PDCD1 (0.43) | PDCD1CD274HTTTDP1FBP1 | |
| SCHEMBL8152443 | 0.79 | POLB (0.40) | POLBAPEX1HTTTDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |