Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 3/20 | 0.42 |
| ▸ | P4HB | P07237 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795700 | 0.79 | P4HB (0.46) | PDCD1CD274FBP1P4HBGRIK1 | |
| SCHEMBL5970511 | 0.77 | PDCD1 (0.53) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL6981746 | 0.74 | AKR1C3 (0.59) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL28372992 | 0.74 | AKR1C3 (0.59) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL5970912 | 0.74 | PDCD1 (0.51) | PDCD1CD274FBP1P4HBGRIN2D | |
| SCHEMBL3115027 | 0.74 | AKR1C3 (0.59) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL5970509 | 0.72 | PDCD1 (0.54) | PDCD1CD274FBP1P4HB | |
| SCHEMBL31546284 | 0.72 | FBP1 (0.54) | PDCD1CD274FBP1P4HBGRIN2D | |
| SCHEMBL5971058 | 0.72 | PDCD1 (0.62) | PDCD1CD274FBP1P4HBKDM4E | |
| SCHEMBL5971061 | 0.72 | PDCD1 (0.62) | PDCD1CD274FBP1P4HBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245564-B1 | BENZAMIDINE DERIVATIVES | SANKYO CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-20040248981-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-12-09 | — | — | US | disclosed |
| US-20040010009-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-01-15 | — | — | US | disclosed |
| US-6555556-B1 | N-(4-(1-acetimidoylpiperidin-4-yl)oxyphenyl)-N-((E)-3-(3 -amidinophenyl)-2-methyl-2-propenyl)sulfamoylacetic acid dihydrochloride for example; factor Xa inhibitors | SANKYO COMPANY, LIMITED (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010009-A1 | Benzamidine derivatives | HABP2, F7, F2 | PDCD1 3406/4885CD274 4342/4885FBP1 594/4885 |
| US-20040248981-A1 | Benzamidine derivatives | HABP2, F7, F2 | PDCD1 3414/4885CD274 4296/4885FBP1 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.