Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971149 | 0.88 | ADORA2B (0.47) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5970088 | 0.88 | ALDH1A1 (0.51) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5970475 | 0.74 | ADORA2B (0.49) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL378878 | 0.72 | ADORA2B (0.58) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL6796625 | 0.71 | ADORA2B (0.48) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5970236 | 0.70 | ADORA2B (0.49) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL9244067 | 0.70 | ADORA2B (0.53) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5970321 | 0.70 | ADORA2A (0.47) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL22119850 | 0.69 | GPR119 (0.54) | GPR119DDB1CRBNOPRM1OPRL1 | |
| SCHEMBL29429688 | 0.69 | ADORA2B (0.43) | ADORA2BADORA3ADORA2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658291-A2 | SUBSTITUTED 8-HETEROARYL XANTHINES | Adenosine Therapeutics, LLC (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005021548-A2 | SUBSTITUTED 8-HETEROARYL XANTHINES | ADENOSINE THERAPEUTICS, LLC (US) | 2005-03-10 | — | — | WO | disclosed |