Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971966 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTTXNRD1HTTGLP1R | |
| SCHEMBL5120739 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTMAPK1HCAR3 | |
| SCHEMBL5120740 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTMAPK1HCAR3 | |
| SCHEMBL5972411 | 0.77 | EGFR (0.40) | ALDH1A1MAPTTXNRD1S1PR4S1PR1 | |
| SCHEMBL5972419 | 0.77 | EGFR (0.40) | ALDH1A1MAPTTXNRD1S1PR4S1PR1 | |
| SCHEMBL31030223 | 0.74 | TSHR (0.44) | ALDH1A1MAPTTXNRD1HTTS1PR4 | |
| SCHEMBL9854834 | 0.69 | MAPT (0.54) | ALDH1A1MAPTHTTMAPK1HCAR3 | |
| SCHEMBL8316618 | 0.68 | MAPT (0.47) | ALDH1A1MAPTTXNRD1HTTBRD4 | |
| SCHEMBL9111109 | 0.68 | MAPT (0.47) | ALDH1A1MAPTTXNRD1HTTBRD4 | |
| SCHEMBL13555267 | 0.67 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685090-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005042464-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2005-05-12 | — | — | WO | disclosed |