Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 4/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 9/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156922 | 0.92 | SLC5A2 (0.58) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL5974952 | 0.88 | SLC5A2 (0.39) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL30529877 | 0.79 | CYP2A6 (0.45) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL155560 | 0.79 | CYP2A6 (0.45) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL156898 | 0.76 | SLC5A2 (0.41) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL5974499 | 0.74 | CYP2C19 (0.38) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL18505674 | 0.74 | SLC5A2 (0.43) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL5973843 | 0.74 | LMNA (0.42) | MAPTLMNAKMT2ATDP1RAB9A | |
| SCHEMBL155881 | 0.74 | SLC5A2 (0.40) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL155572 | 0.74 | SLC5A2 (0.49) | SLC5A2CYP2A6CYP2C9CYP2E1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651658-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012326-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-10 | — | — | WO | disclosed |