SCHEMBL5976313

SCHEMBL5976313

CCCCCCCCN(CCOc1ccc(CC(OCC)C(=O)O)cc1)C(=O)Nc1ccc(F)cc1F

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.58
PPARA Q07869 5/20 0.58
SOAT1 P35610 3/20 0.53
PPARD Q03181 2/20 0.52
SOAT2 O75908 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5980637 1.00 PPARG (0.58) PPARGPPARASOAT1PPARDSOAT2
SCHEMBL5981461 1.00 PPARG (0.58) PPARGPPARASOAT1PPARDSOAT2
SCHEMBL5975706 1.00 PPARG (0.58) PPARGPPARASOAT1PPARDSOAT2
SCHEMBL5980799 1.00 PPARG (0.58) PPARGPPARASOAT1PPARDSOAT2
SCHEMBL5976995 0.99 PPARA (0.57) PPARGPPARASOAT1PPARDSOAT2
SCHEMBL5975687 0.95 PPARA (0.52) PPARGPPARASOAT1PPARD
SCHEMBL5977884 0.94 PPARA (0.52) PPARGPPARASOAT1PPARD
SCHEMBL5976184 0.94 PPARA (0.51) PPARGPPARASOAT1PPARDSOAT2
SCHEMBL5977126 0.93 PPARA (0.50) PPARGPPARASOAT1PPARD
SCHEMBL5979994 0.93 PPARG (0.56) PPARGPPARASOAT1PPARDSOAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015345-B2 Propionic acid derivatives ASAHI KASEI PHARMA CORPORATION (JP) 2006-03-21 US disclosed
EP-1484316-A1 NOVEL PROPIONIC ACID DERIVATIVE Asahi Kasei Pharma Corporation (JP) 2004-12-08 EP disclosed
US-20040072690-A1 Novel propionic acid derivatives ASAHI KASEI PHARMA CORPORATION (JP) 2004-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072690-A1 Novel propionic acid derivatives PNLIP, LIPC, GPR119 PPARG 125/4885PPARA 37/4885SOAT1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.