Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 1.00 |
| ▸ | HTR1A | P08908 | 8/20 | 1.00 |
| ▸ | HTR2A | P28223 | 3/20 | 0.72 |
| ▸ | HTR7 | P34969 | 2/20 | 0.72 |
| ▸ | DRD1 | P21728 | 2/20 | 0.69 |
| ▸ | HTR6 | P50406 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079473 | 1.00 | DRD2 (1.00) | DRD2HTR1AHTR2AHTR7DRD1 | |
| SCHEMBL31029854 | 1.00 | DRD2 (1.00) | DRD2HTR1AHTR2AHTR7DRD1 | |
| SCHEMBL25173335 | 1.00 | DRD2 (1.00) | DRD2HTR1AHTR2AHTR7DRD1 | |
| SCHEMBL29723260 | 1.00 | DRD2 (1.00) | DRD2HTR1AHTR2AHTR7DRD1 | |
| Bromide SCHEMBL11710282 | 0.98 | DRD2 (0.97) | DRD2HTR1AHTR2AHTR7DRD1 | |
| Hydrochloric Acid SCHEMBL11707353 | 0.98 | DRD2 (0.97) | DRD2HTR1AHTR2AHTR7DRD1 | |
| SCHEMBL28809991 | 0.98 | DRD2 (0.97) | DRD2HTR1AHTR2AHTR7DRD1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1203844 | 0.85 | DRD2 (0.73) | DRD2HTR1AHTR2AHTR7DRD1 | |
| Isoquinoline SCHEMBL28350142 | 0.84 | DRD2 (0.71) | DRD2HTR1AHTR2AHTR7DRD1 | |
| SCHEMBL15847729 | 0.84 | DRD2 (0.72) | DRD2HTR1AHTR2AHTR7DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925626-B | Novel aporphine compound and preparation method and application thereof | 中国药科大学 | 2025-06-13 | — | — | CN | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| CN-119588950-A | Preparation method of metal organic coordination polymer mediated silver nanowire | 深圳市源利电子新材料有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119000838-A | Computer-aided isoquinoline alkaloid diagnostic ion acquisition method | 中国科学院大连化学物理研究所 | 2024-11-22 | — | — | CN | claimed |
| CN-118703454-A | Cytochrome P450 enzyme from stephania tetrandra and application thereof in biosynthesis of aporphine alkaloid compound | 中国中医科学院中药研究所 | 2024-09-27 | — | — | CN | claimed |
| US-20240299481-A1 | STEPHANIA CEPHARANTHA-DERIVED ALKALOID-CONTAINING PREPARATION | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 2024-09-12 | — | — | US | claimed |
| CN-118146156-A | Aporphine alkaloid compound, preparation method and application thereof, and pharmaceutical composition | 中国科学院大连化学物理研究所 | 2024-06-07 | — | — | CN | claimed |
| CN-114891840-B | Lotus leaf O-methyltransferase and application of encoding gene thereof in synthesis of benzyl isoquinoline alkaloid and phenylpropionic acid compounds | 中国中医科学院中药研究所 | 2024-04-30 | — | — | CN | claimed |
| CN-115490637-B | Preparation method and application of aporphine alkaloid compound | 海南医学院 | 2024-03-29 | — | — | CN | claimed |
| US-20240102061-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | HERCULES CAPITAL, INC., AS AGENT | 2024-03-28 | — | — | US | claimed |
| EP-1309553-A1 | NEW APORPHINE ESTERS AND THEIR USE IN THERAPY | Axon Biochemicals B.V. (NL) | 2003-05-14 | — | — | EP | claimed |
| WO-2002100377-A1 | PHARMACEUTICAL FORMULATION FOR THE EFFICIENT ADMINISTRATION OF APOMORPHINE, 6aR-(-)-N-PROPYL-NORAPOMORPHINE AND THEIR DERIVATIVES AND PRO-DRUGS THEREOF | AXON BIOCHEMICALS B.V (NL) | 2002-12-19 | — | — | WO | claimed |
| WO-2002014279-A1 | NEW APORPHINE ESTERS AND THEIR USE IN THERAPY | AXON BIOCHEMICALS B.V. (NL) | 2002-02-21 | — | — | WO | claimed |
| US-20010000731-A1 | Method for the prevention and treatment of chronic venous insufficiency | UNIGEN PHARMACEUTICALS, INC. | 2001-05-03 | — | — | US | claimed |
| US-6210680-B1 | ADMINISTRATION TO A PATIENT IN NEED THEREOF AN EFFECTIVE AMOUNT OF AN ISOQUINOLINE ALKALOID. | UNIVERA PHARMACEUTICALS, INC. | 2001-04-03 | — | — | US | claimed |
| WO-2000076526-A1 | METHOD FOR THE PREVENTION AND TREATMENT OF CHRONIC VENOUS INSUFFICIENCY | UNIVERA PHARMACEUTICALS, INC. (US) | 2000-12-21 | — | — | WO | claimed |
| US-6126924-A | Light responsive self-tanning products and methods for use | SCALES-MEDEIROS VIRGINIA A (US) | 2000-10-03 | — | — | US | claimed |
| US-5156847-A | Aporphinoid alkaloid in nonaqueous solvent | Lewis, Walter H. (US) | 1992-10-20 | — | — | US | claimed |
| WO-1990012574-A1 | DOPAMINE AGONIST COMPOUNDS | NORTHEASTERN UNIVERSITY (US) | 1990-11-01 | — | — | WO | claimed |
| US-4013664-A | PSCHORR CYCLIZATION | RESEARCH CORPORATION (US) | 1977-03-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299481-A1 | STEPHANIA CEPHARANTHA-DERIVED ALKALOID-CONTAINING PREPARATION | SARS1, BCDIN3D, CCL5 | DRD2 2333/4885HTR1A 1355/4885HTR2A 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.