SCHEMBL59809

SCHEMBL59809

Nc1nc(C[C@H](N)C(=O)O)c[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.46
CYP3A4 P08684 3/20 0.46
CYP1A2 P05177 1/20 0.45
KDM4E B2RXH2 3/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
BLM P54132 3/20 0.42
PMP22 Q01453 3/20 0.42
KMT2A Q03164 3/20 0.42
TSHR P16473 2/20 0.42
MEN1 O00255 2/20 0.42
HIF1A Q16665 2/20 0.42
MPO P05164 1/20 0.42
PKM P14618 2/20 0.42
ALPI P09923 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59808 1.00 SLC7A5 (0.46) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL25660495 0.83 SLC7A5 (0.46) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL15349976 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL1065159 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL10404524 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL1065160 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL1539193 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL4854899 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL4854895 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL11152703 0.81 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103499-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (US) 2026-04-16 US claimed
US-20250122239-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2025-04-17 US claimed
WO-2025069009-A1 ROCK2 INHIBITORS IN THE TREATMENT OF OBESITY GRAVITON BIOSCIENCE BV (NL) 2025-04-03 WO claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
EP-3891176-B1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2024-06-05 EP claimed
CN-117778530-A Method for adding preset joint to 5' end of single-stranded DNA 清华大学 2024-03-29 CN claimed
EP-3250191-B1 TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING NOVO NORDISK AS (DK) 2024-01-17 EP claimed
EP-3077008-B1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (CN) 2023-10-04 EP claimed
CN-112043835-B Bioreversible introducing group for nitrogen and hydroxyl-containing drugs 韩捷 2022-10-21 CN claimed
EP-2637698-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2022-04-20 EP claimed
WO-2001098331-A2 GLUCAGON-LIKE PEPTIDE-1 ANALOGS ELI LILLY AND COMPANY (US) 2001-12-27 WO claimed
US-6277819-B1 GLUCAGON LIKE PEPTIDE1 (GLP-1) USED TO NORMALIZE BLOOD GLUCOSE IN DIABETIC PATIENTS ELI LILLY AND COMPANY 2001-08-21 US claimed
EP-1049486-A1 GLP-1 FORMULATIONS ELI LILLY AND COMPANY (US) 2000-11-08 EP claimed
US-6133235-A FOR TREATING MATURITY ONSET DIABETES MELLITUS IN MAMMALS, PARTICULARLY HUMANS ELI LILLY AND COMPANY (US) 2000-10-17 US claimed
US-5981488-A POLYPEPTIDE; ANTIDIABETIC AGENT ELI LILLLY AND COMPANY (US) 1999-11-09 US claimed
US-5977071-A COMPLEXES; ANTIDIABETIC AGENT ELI LILLY AND COMPANY (US) 1999-11-02 US claimed
WO-1999029336-A1 GLP-1 FORMULATIONS ELI LILLY AND COMPANY (US) 1999-06-17 WO claimed
WO-1998043658-A1 GLUCAGON-LIKE PEPTIDE-1 ANALOGS ELI LILLY AND COMPANY (US) 1998-10-08 WO claimed
EP-0869135-A1 Glucagon-like peptide-1 analogs ELI LILLY AND COMPANY (US) 1998-10-07 EP claimed
EP-0733644-A1 Glucagon-like insulinotropic complexes, compositions and methods ELI LILLY AND COMPANY (US) 1996-09-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103499-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS CBR1, CBR3, SIGMAR1 SLC7A5 424/4885CYP3A4 59/4885CYP1A2 212/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 SLC7A5 66/4885CYP3A4 3633/4885CYP1A2 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.