Sugi Predict

Sugi Predict / Compounds / SCHEMBL5980930

SCHEMBL5980930

SCHEMBL5980930

CCCCCCCC/C=C\CCCCCCCCC(O)(CCCCCCCC/C=C\CCCCCCCC)[C@@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.46
▸ SPHK2 Q9NRA0 4/20 0.46
▸ SPHK1 Q9NYA1 4/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ CETP P11597 3/20 0.46
▸ MAPK1 P28482 3/20 0.46
▸ CYP2D6 P10635 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ GMNN O75496 2/20 0.46
▸ LMNA P02545 2/20 0.46
▸ GLA P06280 2/20 0.46
▸ POLB P06746 2/20 0.46
▸ THRB P10828 2/20 0.46
▸ CXCR5 P32302 2/20 0.46
▸ CCR6 P51684 2/20 0.46
▸ BLM P54132 2/20 0.46
▸ UBE2N P61088 2/20 0.46
▸ TP53 P04637 2/20 0.46
▸ CYP1A2 P05177 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591410 1.00 MAPT (0.46) MAPTSPHK2SPHK1MEN1KMT2A
SCHEMBL1735175 1.00 MAPT (0.46) MAPTSPHK2SPHK1MEN1KMT2A
SCHEMBL7202725 1.00 MAPT (0.46) MAPTSPHK2SPHK1MEN1KMT2A
SCHEMBL16086046 1.00 MAPT (0.46) MAPTSPHK2SPHK1MEN1KMT2A
SCHEMBL11459957 0.97 MAPT (0.44) MAPTSPHK2SPHK1MEN1KMT2A
SCHEMBL3892975 0.93 ALDH1A1 (0.50) MAPTALDH1A1THRBBLMCNR1
SCHEMBL25815 0.89 LMNA (0.41) MAPTSPHK1MEN1KMT2ACETP
SCHEMBL2226505 0.89 LMNA (0.41) MAPTSPHK1MEN1KMT2ACETP
SCHEMBL18863212 0.89 LMNA (0.41) MAPTSPHK1MEN1KMT2ACETP
SCHEMBL142854 0.89 LMNA (0.41) MAPTSPHK1MEN1KMT2ACETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7067697-B2 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY (US) 2006-06-27 — — US disclosed
US-20060057194-A1 Cationic liposomes for gene transfer GAO XIANG 2006-03-16 — — US disclosed
US-7002042-B2 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY (US) 2006-02-21 — — US disclosed
US-20040038883-A1 Peptide inhibitors of Akt and uses thereof PORTER ATHLETIC EQUIPMENT COMPANY 2004-02-26 — — US disclosed
US-6656498-B1 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY 2003-12-02 — — US disclosed
US-20030049310-A1 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY 2003-03-13 — — US disclosed
WO-2000030444-A1 CATIONIC LIPOSOMES FOR GENE TRANSFER VANDERBILT UNIVERSITY (US) 2000-06-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060057194-A1 Cationic liposomes for gene transfer LCLAT1, LPCAT3, LPCAT1 MAPT 4817/4885SPHK2 163/4885SPHK1 228/4885
US-20030049310-A1 Cationic liposomes for gene transfer LCLAT1, LPCAT3, LPCAT1 MAPT 4817/4885SPHK2 163/4885SPHK1 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.