Sugi Predict

Sugi Predict / Compounds / SCHEMBL142854

SCHEMBL142854

SCHEMBL142854

CCCCCCCCCCCCC(O)(CCCCCCCCCCCC)C(O)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.41
▸ FDPS P14324 8/20 0.41
▸ GGPS1 O95749 5/20 0.41
▸ CYP2D6 P10635 2/20 0.39
▸ SPHK1 Q9NYA1 1/20 0.39
▸ GMNN O75496 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CETP P11597 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ UBE2N P61088 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28434703 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL18863212 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL1890334 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL5820256 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL25815 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL2226505 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL5963212 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL139952 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL136611 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1
SCHEMBL29064953 1.00 LMNA (0.41) LMNAFDPSGGPS1CYP2D6SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352666-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO (US) 2025-11-20 — — US claimed
EP-4626409-A1 SYNTHETIC SINGLE STRANDED NUCLEIC ACID COMPOSITIONS AND METHODS THEREOF Generation Bio Co. (US) 2025-10-08 — — EP claimed
US-20250249123-A1 LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. 2025-08-07 — — US claimed
WO-2025127402-A1 LIPID FOR ENHANCING IMMUNOGENICITY OF MRNA/LNP VACCINE 한국생명공학연구원 2025-06-19 — — WO claimed
EP-4536197-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF Generation Bio Co. (US) 2025-04-16 — — EP claimed
US-12263228-B2 Lipids and compositions thereof GENERATION BIO CO. (US) 2025-04-01 — — US claimed
WO-2024249298-A2 MODIFIED CLOSED-ENDED DNA (CEDNA) VECTORS, COMPOSITIONS, AND USES THEREOF GENERATION BIO CO. (US) 2024-12-05 — — WO claimed
US-20240382432-A1 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. 2024-11-21 — — US claimed
US-20240299580-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. 2024-09-12 — — US claimed
US-20240293574-A1 CATIONIC LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. 2024-09-05 — — US claimed
EP-4370135-A2 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF Generation Bio Co. (US) 2024-05-22 — — EP claimed
EP-4355727-A1 CATIONIC LIPIDS AND COMPOSITIONS THEREOF Generation Bio Co. (US) 2024-04-24 — — EP claimed
EP-4351533-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF Generation Bio Co. (US) 2024-04-17 — — EP claimed
EP-4326235-A2 CATIONIC LIPIDS AND COMPOSITIONS THEREOF Generation Bio Co. (US) 2024-02-28 — — EP claimed
WO-2023239756-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. (US) 2023-12-14 — — WO claimed
WO-2023287861-A2 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. (US) 2023-01-19 — — WO claimed
WO-2022266032-A1 CATIONIC LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. (US) 2022-12-22 — — WO claimed
WO-2022261101-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. (US) 2022-12-15 — — WO claimed
WO-2022226008-A2 CATIONIC LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. (US) 2022-10-27 — — WO claimed
WO-2002087541-A1 LIPID-BASED FORMULATIONS FOR GENE TRANSFER PROTIVA BIOTHERAPEUTICS INC. (CA) 2002-11-07 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299580-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LDLR, APOB, APOL1 LMNA 63/4885FDPS 3983/4885GGPS1 4063/4885
US-12263228-B2 Lipids and compositions thereof C1R, LIPG, LRBA LMNA 49/4885FDPS 2553/4885GGPS1 3358/4885
US-20250352666-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, EYA3, EYA2 LMNA 305/4885FDPS 2386/4885GGPS1 1556/4885
US-20250249123-A1 LIPIDS AND COMPOSITIONS THEREOF C1R, LIPG, LRBA LMNA 49/4885FDPS 2553/4885GGPS1 3358/4885
US-20240293574-A1 CATIONIC LIPIDS AND COMPOSITIONS THEREOF LIPG, LRBA, PCNP LMNA 27/4885FDPS 3978/4885GGPS1 3781/4885
US-20240382432-A1 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LNPEP, CD47, CD4 LMNA 800/4885FDPS 3569/4885GGPS1 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.