SCHEMBL5981301

SCHEMBL5981301

Cc1c(O)cc2oc(-c3ccc(O)c(O)c3)cc(=O)c2c1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 2/20 0.73
▸ KMT2A Q03164 4/20 0.70
▸ KDM4E B2RXH2 3/20 0.70
▸ MEN1 O00255 3/20 0.70
▸ MAPT P10636 3/20 0.70
▸ RECQL P46063 3/20 0.70
▸ AMY1A P0DUB6 3/20 0.70
▸ POLB P06746 2/20 0.70
▸ GAA P10253 2/20 0.70
▸ THRB P10828 2/20 0.70
▸ BLM P54132 2/20 0.70
▸ NPC1 O15118 1/20 0.70
▸ APEX1 P27695 1/20 0.70
▸ CASP6 P55212 1/20 0.70
▸ GFER P55789 1/20 0.70
▸ POLH Q9Y253 4/20 0.64
▸ CYP3A4 P08684 2/20 0.64
▸ ALOX5 P09917 2/20 0.64
▸ CYP2C9 P11712 2/20 0.64
▸ ALOX15 P16050 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20718935 0.88 ABCB1 (0.71) ABCB1KMT2AKDM4EMEN1MAPT
SCHEMBL515131 0.87 ABCB1 (0.80) ABCB1KMT2AKDM4EMEN1MAPT
6-Hydroxyluteolin SCHEMBL29929561 0.87 KMT2A (0.76) ABCB1KMT2AKDM4EMEN1MAPT
6-Hydroxyluteolin SCHEMBL29887622 0.87 KMT2A (0.76) ABCB1KMT2AKDM4EMEN1MAPT
6-Hydroxyluteolin SCHEMBL30217544 0.87 KMT2A (0.76) ABCB1KMT2AKDM4EMEN1MAPT
6-Hydroxyluteolin SCHEMBL1155724 0.87 KMT2A (0.76) ABCB1KMT2AKDM4EMEN1MAPT
SCHEMBL6245328 0.84 ABCB1 (1.00) ABCB1KMT2AKDM4EMEN1MAPT
SCHEMBL16088300 0.83 HDAC6 (0.78) ABCB1KMT2AKDM4EMEN1MAPT
Eupafolin SCHEMBL29929325 0.83 MEN1 (1.00) KMT2AKDM4EMEN1MAPTRECQL
Eupafolin SCHEMBL29915043 0.83 MEN1 (1.00) KMT2AKDM4EMEN1MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104529975-B Corm Eleocharitis skin extracts the method for 6-methyl luteolin 贺州学院 2016-07-06 — — CN claimed
CN-104529975-A Method for extracting 6-methylluteolin from eleocharis tuberose peels UNIV HEZHOU 2015-04-22 — — CN claimed
CN-119335102-A Method for detecting traditional Chinese medicine source components in pinecone alcohol extract 大理大学 2025-01-21 — — CN disclosed
US-9415034-B2 Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B) NATIONAL DEFENSE MEDICAL CENTER (TW) 2016-08-16 — — US disclosed
CN-104529975-B Corm Eleocharitis skin extracts the method for 6-methyl luteolin 贺州学院 2016-07-06 — — CN disclosed
CN-104529975-B Corm Eleocharitis skin extracts the method for 6-methyl luteolin 贺州学院 2016-07-06 — — CN disclosed
CN-104529975-B Corm Eleocharitis skin extracts the method for 6-methyl luteolin 贺州学院 2016-07-06 — — CN disclosed
US-20160184298-A1 INHIBITORS AND ENHANCERS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE 2B (UGT2B) NAT DEFENSE MEDICAL CT (TW) 2016-06-30 — — US disclosed
US-9265808-B2 Compositions for alleviating inflammation and oxidative stress in a mammal LIFELINE NUTRACEUTICALS CORPORATION (US) 2016-02-23 — — US disclosed
US-20150283193-A9 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal LIFELINE NUTRACEUTICALS (US) 2015-10-08 — — US disclosed
CN-104529975-A Method for extracting 6-methylluteolin from eleocharis tuberose peels UNIV HEZHOU 2015-04-22 — — CN disclosed
CN-1658757-A Antihelminthic anthraquinones and method of use thereof UNIV MICHIGAN (US) 2005-08-24 — — CN disclosed
US-6903076-B2 Antihelminthic anthraquinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-06-07 — — US disclosed
US-6838443-B2 Antihelminthic anthraquinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-01-04 — — US disclosed
US-6800615-B2 PARASITICIDES, NEMATOCIDES BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2004-10-05 — — US disclosed
US-20040152645-A1 Antihelminthic anthraquinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2004-08-05 — — US disclosed
US-20040116361-A1 Antihelminthic anthraquinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2004-06-17 — — US disclosed
US-20040106686-A1 Antihelminthic anthraquinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2004-06-03 — — US disclosed
US-20030229032-A1 Antihelminthic anthraquinones and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2003-12-11 — — US disclosed
WO-2003089577-A2 ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2003-10-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229032-A1 Antihelminthic anthraquinones and method of use thereof HRH2, HRH3, HRH1 ABCB1 1577/4885KMT2A 703/4885KDM4E 1098/4885
US-20040152645-A1 Antihelminthic anthraquinones and method of use thereof HRH2, HRH3, HRH1 ABCB1 1577/4885KMT2A 703/4885KDM4E 1098/4885
US-20160184298-A1 INHIBITORS AND ENHANCERS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE 2B (UGT2B) UGT2B7, UGT2B17, UGT1A10 ABCB1 18/4885KMT2A 4826/4885KDM4E 4425/4885
US-20150283193-A9 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal GSTO1, GSTK1, GSTP1 ABCB1 2413/4885KMT2A 658/4885KDM4E 2166/4885
US-20040106686-A1 Antihelminthic anthraquinones and method of use thereof HRH2, HRH3, HRH1 ABCB1 1577/4885KMT2A 703/4885KDM4E 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback