Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681167 | 1.00 | MAPT (0.51) | MAPTLMNATDP1KMT2AMAPK1 | |
| SCHEMBL26290435 | 0.86 | MAPT (0.50) | MAPTLMNATDP1KMT2AMAPK1 | |
| SCHEMBL25427561 | 0.84 | ALDH1A1 (0.49) | MAPTLMNATDP1KMT2AMAPK1 | |
| Ethyl Nicotinate SCHEMBL502614 | 0.84 | L3MBTL1 (0.51) | MAPTLMNATDP1KMT2AMAPK1 | |
| SCHEMBL9245476 | 0.84 | ALDH1A1 (0.49) | TDP1MAPK1ALDH1A1GAAHPGD | |
| SCHEMBL26455064 | 0.84 | ALDH1A1 (0.49) | TDP1MAPK1ALDH1A1GAAHPGD | |
| SCHEMBL9245472 | 0.84 | ALDH1A1 (0.49) | TDP1MAPK1ALDH1A1GAAHPGD | |
| Niacinamide SCHEMBL17318207 | 0.83 | F7 (0.51) | MAPTLMNATDP1KMT2AMAPK1 | |
| SCHEMBL15562680 | 0.82 | HK1 (0.43) | TDP1ALDH1A1HPGD | |
| SCHEMBL15562678 | 0.82 | HK1 (0.43) | TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132402-B2 | Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation | WYETH (US) | 2006-11-07 | — | — | US | claimed |
| US-7132402-B2 | Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation | WYETH (US) | 2006-11-07 | — | — | US | disclosed |
| US-20050176652-A1 | Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation | WYETH (US) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176652-A1 | Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation | MYLK, TNNI3, MYLK2 | MAPT 4877/4885LMNA 1766/4885TDP1 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.