Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782150 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL4857963 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL4856578 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL7388648 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5780390 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL870500 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5419204 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL869390 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5766977 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5821038 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138533-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-21 | — | — | US | disclosed |
| US-20050197362-A1 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197362-A1 | Preventives/remedies for urinary disturbance | ACHE, BPHL, CHRM1 | ALDH1A1 118/4885KDM4E 3792/4885HPGD 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.