Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782150 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL4857963 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5981634 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL4856578 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5780390 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL27593143 | 0.80 | ADRB2 (0.48) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL27593179 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTTSHRSMN1; SMN2 | |
| SCHEMBL27611658 | 0.80 | ACHE (0.54) | ALDH1A1KDM4EHPGDRECQLMAPT | |
| SCHEMBL5766977 | 0.80 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM | |
| SCHEMBL5821038 | 0.80 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDRECQLNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114028-A1 | AZA-BICYCLES WHICH MODULATE THE INHIBITION OF CELL ADHESION | Aventis Pharma Limited (GB) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015612-A1 | AZA-BICYCLES WHICH MODULATE THE INHIBITION OF CELL ADHESION | AVENTIS PHARMA LIMITED (GB) | 2000-03-23 | — | — | WO | disclosed |