Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42251 | 0.82 | TSHR (0.34) | FDPSTSHRHPGDMEN1CYP1A2 | |
| SCHEMBL3271689 | 0.77 | CES2 (0.36) | TSHRMEN1KMT2AZDHHC20ZDHHC2 | |
| SCHEMBL7027146 | 0.77 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL11358946 | 0.76 | TSHR (0.36) | TSHRHPGDMEN1KMT2AZDHHC20 | |
| SCHEMBL5280547 | 0.76 | CES2 (0.39) | FDPSTSHRFAAHMEN1KMT2A | |
| SCHEMBL7059895 | 0.73 | CES2 (0.40) | FDPSTSHRFAAHMEN1KMT2A | |
| SCHEMBL10757979 | 0.73 | CES2 (0.40) | TSHRMEN1KMT2AZDHHC20ZDHHC2 | |
| SCHEMBL11042964 | 0.72 | TSHR (0.33) | TSHRHPGDFAAHZDHHC20ZDHHC2 | |
| SCHEMBL4209537 | 0.71 | MBOAT4 (0.41) | FAAHMEN1CYP3A4CYP2C19KMT2A | |
| SCHEMBL15859490 | 0.71 | CES2 (0.41) | FDPSTSHRFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135384-A1 | MULTI-COMPONENT PARTICLES COMPRISING INORGANIC NANOPARTICLES DISTRIBUTED IN AN ORGANIC MATRIX AND PROCESSES FOR MAKING AND USING SAME | CABOT CORPORATION (US) | 2006-12-21 | — | — | WO | disclosed |