Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598409 | 0.86 | KDM4E (0.43) | MEN1KMT2A | |
| SCHEMBL598830 | 0.85 | ACP3 (0.49) | CHRM1EPHX1BACE1BACE2ACP3 | |
| SCHEMBL600006 | 0.79 | TACR3 (0.43) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL599493 | 0.71 | AKR1B1 (0.39) | KMT2A | |
| SCHEMBL599640 | 0.70 | KDM4E (0.45) | MEN1KMT2A | |
| SCHEMBL598171 | 0.70 | UTS2R (0.38) | ACP3MEN1KMT2A | |
| SCHEMBL599408 | 0.69 | TDP1 (0.49) | CYP1A2PPARGMEN1KMT2A | |
| SCHEMBL14691416 | 0.69 | CHRM1 (0.63) | CHRM1EPHX1ESR1ESR2UBE2N | |
| SCHEMBL10691182 | 0.69 | EPHX1 (0.61) | CHRM1EPHX1ACP3ESR1ESR2 | |
| SCHEMBL14384902 | 0.69 | EPHX1 (0.61) | CHRM1EPHX1ACP3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |