Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600006 | 0.91 | TACR3 (0.43) | AKR1B1TDP1L3MBTL1TACR3PTGS2 | |
| SCHEMBL598171 | 0.89 | UTS2R (0.38) | AKR1B1TDP1L3MBTL1TACR3PTGS2 | |
| SCHEMBL599408 | 0.88 | TDP1 (0.49) | TDP1L3MBTL1PTGS2MGAMGAA | |
| SCHEMBL598815 | 0.84 | RAB9A (0.39) | AKR1B1L3MBTL1GAAKMT2AAKR1C3 | |
| SCHEMBL17681437 | 0.79 | ALDH1A1 (0.40) | KMT2AMAPTHPGD | |
| SCHEMBL30532623 | 0.76 | LMNA (0.45) | PTGS2PGRPTGS1PDE4AKMT2A | |
| SCHEMBL598409 | 0.74 | KDM4E (0.43) | TDP1L3MBTL1GAAKMT2AMAPT | |
| SCHEMBL17681406 | 0.74 | ALDH1A1 (0.39) | AKR1B1PTGS2PTGS1HPGDAKR1C3 | |
| SCHEMBL599730 | 0.74 | ALDH1A1 (0.47) | AKR1B1PTGS2GAAPTGS1HPGD | |
| SCHEMBL600002 | 0.73 | UTS2R (0.44) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |