Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598830 | 0.85 | ACP3 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL598409 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1LMNAGAAMEN1 | |
| SCHEMBL599730 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAGAASLC6A4 | |
| SCHEMBL30532627 | 0.81 | GAA (0.51) | KDM4EALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL16000084 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL21846116 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL20083856 | 0.77 | KMT2A (0.43) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL17681440 | 0.77 | MEN1 (0.46) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL16984827 | 0.76 | HPGD (0.50) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL447136 | 0.76 | CYP2C9 (0.48) | ALDH1A1TDP1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |