Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598317 | 0.86 | CHRM1 (0.45) | MEN1KMT2A | |
| SCHEMBL599640 | 0.84 | KDM4E (0.45) | KDM4EMEN1KMT2ALMNATDP1 | |
| SCHEMBL600006 | 0.83 | TACR3 (0.43) | KDM4EMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29272525 | 0.79 | MEN1 (0.44) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30532627 | 0.79 | GAA (0.51) | KDM4EMEN1KMT2ALMNACRHBP | |
| SCHEMBL599493 | 0.74 | AKR1B1 (0.39) | KMT2AMAPTTDP1L3MBTL1GAA | |
| SCHEMBL598171 | 0.73 | UTS2R (0.38) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL2290954 | 0.73 | CRHBP (0.53) | KDM4EMEN1KMT2ALMNACRHBP | |
| SCHEMBL599408 | 0.72 | TDP1 (0.49) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL598410 | 0.72 | AKR1C3 (0.38) | KDM4EMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |