Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 6/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945967 | 0.90 | KMT2A (0.39) | KMT2ARARBMMP8ALDH1A1ACACB | |
| SCHEMBL5982548 | 0.84 | PTGER4 (0.45) | KMT2AMMP8ADRB1ADRB3MEN1 | |
| SCHEMBL5982493 | 0.83 | PTGER4 (0.48) | KMT2ARARBALDH1A1MEN1RARA | |
| SCHEMBL5988841 | 0.83 | ALDH1A1 (0.41) | KMT2AALDH1A1ADRB1ADRB3MEN1 | |
| SCHEMBL5983445 | 0.83 | PTGER4 (0.40) | ALDH1A1MAPTHTTSMN1; SMN2PTGER4 | |
| SCHEMBL5982781 | 0.82 | EPHX1 (0.38) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL5982183 | 0.79 | ADAM17 (0.41) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5981555 | 0.79 | ACACB (0.47) | ACACBMMP12PTGER4PTGER2 | |
| SCHEMBL5983075 | 0.79 | PTGER4 (0.51) | ADRB1ADRB3MTORPTGER4PTGER2 | |
| SCHEMBL5983282 | 0.79 | BCL2 (0.43) | ADRB1ADRB3PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |