Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.39 |
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31452714 | 0.79 | PTPN1 (0.56) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL31452723 | 0.79 | NOS2 (0.38) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL17520300 | 0.79 | PTPN2 (0.43) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL18306890 | 0.76 | DAPK3 (0.36) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL31377558 | 0.75 | PTPN1 (0.61) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL86743 | 0.72 | NOS2 (0.48) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL23430641 | 0.71 | PTGS2 (0.46) | KDM4EALDH1A1GAANPC1RAD51 | |
| SCHEMBL23430642 | 0.71 | SMN1; SMN2 (0.46) | KDM4EALDH1A1GAANPC1PTGS2 | |
| SCHEMBL5494150 | 0.68 | MAPT (0.36) | KDM4EALDH1A1GAACASP1CASP7 | |
| SCHEMBL20610627 | 0.67 | CDK2 (0.40) | KDM4EALDH1A1GAAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732509-A1 | KERATIN DYEING COMPOSITIONS BICYCLIC 5-6 HETEROAROMATIC DYEING COMPOUNDS WITH ONE RING NITROGEN JUNCTION | The Procter and Gamble Company (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097052-A1 | KERATIN DYEING COMPOSITIONS BICYCLIC 5-6 HETEROAROMATIC DYEING COMPOUNDS WITH ONE RING NITROGEN JUNCTION | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-20 | — | — | WO | disclosed |