Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.40 |
| ▸ | CES1 | P23141 | 8/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL600672 | 0.97 | EGFR (0.41) | CES2CES1ABCB1EGFRRAB9A | |
| Bromide SCHEMBL599217 | 0.97 | CES2 (0.40) | CES2CES1ABCB1EGFRRAB9A | |
| Trimethylammonium SCHEMBL600110 | 0.88 | RAB9A (0.46) | CES2CES1EGFRRAB9AMAPT | |
| Trimethylammonium SCHEMBL27704220 | 0.87 | RAB9A (0.45) | CES2CES1EGFRRAB9AMAPT | |
| SCHEMBL2065186 | 0.86 | CES2 (0.54) | CES2CES1RAB9AMAPTKDM4E | |
| Trimethylammonium SCHEMBL597991 | 0.85 | RAB9A (0.46) | CES2CES1EGFRRAB9AMAPT | |
| Trimethylammonium SCHEMBL598821 | 0.85 | RAB9A (0.46) | CES2CES1EGFRRAB9AMAPT | |
| Water SCHEMBL6094264 | 0.85 | CES2 (0.52) | CES2CES1RAB9AMAPTKDM4E | |
| Ammonia Solution, Strong SCHEMBL4936520 | 0.85 | CES2 (0.52) | CES2CES1RAB9AMAPTKDM4E | |
| Benzil SCHEMBL4351569 | 0.79 | CES2 (0.64) | CES2CES1EGFRRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114933-B2 | Thermoplastic resin composition with low coefficient of linear thermal expansion | CHEIL INDUSTRIES INC. (KR) | 2012-02-14 | — | — | US | disclosed |
| EP-1828306-B1 | ABS RESIN COMPOSITION WITH LOW COEFFICIENT OF LINEAR THERMAL EXPANSION | CHEIL IND INC (KR) | 2009-04-08 | — | — | EP | disclosed |
| EP-1828306-A4 | ABS RESIN COMPOSITION WITH LOW COEFFICIENT OF LINEAR THERMAL EXPANSION | CHEIL IND INC (KR) | 2008-08-13 | — | — | EP | disclosed |
| US-20070260013-A1 | Thermoplastic resin composition with low coefficient of linear thermal expansion | CHEIL INDUSTRIES INC (KR) | 2007-11-08 | — | — | US | disclosed |
| EP-1828306-A1 | ABS RESIN COMPOSITION WITH LOW COEFFICIENT OF LINEAR THERMAL EXPANSION | Cheil Industries Inc. (KR) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059814-A1 | ABS RESIN COMPOSITION WITH LOW COEFFICIENT OF LINEAR THERMAL EXPANSION | CHEIL INDUSTRIES INC. (KR) | 2006-06-08 | — | — | WO | disclosed |