Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533170 | 0.89 | L3MBTL1 (0.55) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL6526024 | 0.89 | L3MBTL1 (0.55) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL6528089 | 0.85 | NPSR1 (0.53) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5100806 | 0.84 | L3MBTL1 (0.52) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5096849 | 0.81 | L3MBTL1 (0.50) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5096847 | 0.81 | L3MBTL1 (0.50) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5109895 | 0.80 | L3MBTL1 (0.48) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5100623 | 0.79 | L3MBTL1 (0.48) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5100614 | 0.79 | L3MBTL1 (0.48) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5097012 | 0.79 | L3MBTL1 (0.48) | LMNAKDM4EL3MBTL1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771441-B8 | NOVEL CARBOXAMIDES FOR USE AS XA INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2012-02-15 | — | — | EP | disclosed |
| EP-1771441-A1 | NOVEL CARBOXAMIDES FOR USE AS XA INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2005082895-A1 | NOVEL CARBOXAMIDES FOR USE AS XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-09-09 | — | — | WO | disclosed |