Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598669 | 0.85 | LMNA (0.53) | KDM4ELMNAALDH1A1L3MBTL1TAS1R3 | |
| SCHEMBL6526024 | 0.85 | L3MBTL1 (0.55) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6533170 | 0.85 | L3MBTL1 (0.55) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5101081 | 0.82 | L3MBTL1 (0.47) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5101086 | 0.82 | L3MBTL1 (0.47) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5100806 | 0.78 | L3MBTL1 (0.52) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5096847 | 0.78 | L3MBTL1 (0.50) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5096849 | 0.78 | L3MBTL1 (0.50) | KDM4ELMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL1479881 | 0.77 | DDR1 (0.44) | KDM4ELMNAL3MBTL1TDP1DDR1 | |
| SCHEMBL1481058 | 0.77 | DDR1 (0.52) | KDM4ELMNAALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | claimed |