Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988291 | 0.83 | PPARG (0.35) | — | |
| SCHEMBL5988618 | 0.79 | CA9 (0.31) | KDM4EPOLBMAPTHSD17B10MAP2K1 | |
| Oxalic Acid SCHEMBL5987052 | 0.73 | GAA (0.32) | P4HB | |
| SCHEMBL5988442 | 0.73 | PTGS1 (0.37) | KDM4EPOLBMAPTHSD17B10MAOA | |
| SCHEMBL5987778 | 0.72 | ALDH1A1 (0.31) | P4HBKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL5987127 | 0.72 | MAPT (0.36) | KDM4EPOLBMAPTHSD17B10MAOA | |
| SCHEMBL5986973 | 0.72 | P4HB (0.33) | P4HBKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL5986481 | 0.72 | P4HB (0.31) | P4HBMAOA | |
| Oxalic Acid SCHEMBL5987258 | 0.71 | P4HB (0.32) | P4HBKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL5987440 | 0.71 | DPP4 (0.33) | KDM4EPOLBMAPTHSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045545-B1 | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists | ELI LILLY AND COMPANY (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1149085-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |