Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987778 | 0.79 | ALDH1A1 (0.31) | P4HBKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL5987776 | 0.79 | HTR1B (0.34) | POLBHTR1B | |
| SCHEMBL25528821 | 0.79 | TRPA1 (0.36) | P4HBTRPA1 | |
| Oxalic Acid SCHEMBL5987258 | 0.78 | P4HB (0.32) | P4HBKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL5986108 | 0.78 | KDM4E (0.35) | P4HBKDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL5988125 | 0.76 | P4HB (0.33) | P4HBTRPA1 | |
| SCHEMBL5986612 | 0.75 | P4HB (0.32) | P4HBTRPA1 | |
| Hydrochloric Acid SCHEMBL5987094 | 0.75 | P4HB (0.32) | P4HBTRPA1 | |
| SCHEMBL5988618 | 0.73 | CA9 (0.31) | KDM4EPOLBMAPTHSD17B10 | |
| Fumaric Acid SCHEMBL5987263 | 0.72 | NPSR1 (0.34) | P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045545-B1 | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists | ELI LILLY AND COMPANY (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1149085-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |