Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.51 |
| ▸ | WNT3A | P56704 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82761 | 0.93 | KDM4E (0.62) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL29962256 | 0.91 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL30404733 | 0.91 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL5071439 | 0.91 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL2175299 | 0.91 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Oxalic Acid SCHEMBL6033591 | 0.88 | FLT3 (0.58) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Trifluoroacetic Acid SCHEMBL15546473 | 0.84 | FLT3 (0.54) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL1962245 | 0.81 | CYP1A2 (0.54) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL28388762 | 0.80 | KDM4E (0.49) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL7668372 | 0.78 | KDM4E (0.66) | KDM4EYTHDC1STAT3HIF1AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |