SCHEMBL82761

SCHEMBL82761

NC(=O)c1n[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.62
YTHDC1 Q96MU7 1/20 0.62
STAT3 P40763 1/20 0.62
HIF1A Q16665 1/20 0.62
FLT3 P36888 2/20 0.58
CDK2 P24941 2/20 0.58
CCNA2 P20248 1/20 0.58
CCNA1 P78396 1/20 0.58
CTNNB1 P35222 3/20 0.57
WNT3A P56704 3/20 0.57
IDO1 P14902 1/20 0.55
PDPK1 O15530 1/20 0.53
CYP3A4 P08684 1/20 0.53
GAA P10253 1/20 0.53
NPC1 O15118 4/20 0.53
RAB9A P51151 3/20 0.53
EPHB3 P54753 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 1/20 0.51
CSNK2A1 P68400 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2175299 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL30404733 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL29962256 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL5071439 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Oxalic Acid SCHEMBL6033591 0.95 FLT3 (0.58) KDM4EYTHDC1STAT3HIF1AFLT3
Formic Acid SCHEMBL5987899 0.93 KDM4E (0.55) KDM4EYTHDC1STAT3HIF1AFLT3
Trifluoroacetic Acid SCHEMBL15546473 0.90 FLT3 (0.54) KDM4EYTHDC1STAT3HIF1AFLT3
SCHEMBL1962245 0.87 CYP1A2 (0.54) KDM4EYTHDC1STAT3HIF1AFLT3
SCHEMBL28388762 0.86 KDM4E (0.49) KDM4EYTHDC1STAT3HIF1AFLT3
SCHEMBL31148407 0.84 KDM4E (0.66) KDM4EYTHDC1STAT3HIF1AFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597184-B1 INDANONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS OR OPTICAL ISOMERS THEREOF, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING VIRAL DISEASES KOREA RES INST CHEMICAL TECH (KR) 2026-03-04 EP claimed
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN claimed
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
US-20250243181-A2 NOVEL INDAZOLE DERIVATIVE AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-07-31 US claimed
CN-119907790-A Pyrazole amide insecticidal agents FMC公司 2025-04-29 CN claimed
CN-119907626-A Compositions having pesticidal utility and methods related thereto 科迪华农业科技有限责任公司 2025-04-29 CN claimed
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE METREA BIOSCIENCES INC (US) 2025-03-20 US claimed
CN-119136797-A CB1Ligand conjugated compounds and uses thereof 阿达尔克斯制药有限公司 2024-12-13 CN claimed
EP-4469461-A1 TETRAHYDROPYRANOPYRAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER AND VIRAL INFECTIONS Genase Therapeutics B.V. (NL) 2024-12-04 EP claimed
EP-4186894-B1 FGFR INHIBITOR COMPOUND AND USE THEREOF HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN) 2024-12-04 EP claimed
EP-0975623-B1 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS ACRAF (IT) 2002-06-19 EP claimed
WO-2002036114-A1 COMPOSITION COMPRISING SEROTONIN RECEPTOR ANTAGONISTS, 5 HT-2 AND 5 HT-3 RESPIRATORIUS AB (SE) 2002-05-10 WO claimed
WO-2002036113-A1 COMPOSITION COMPRISING: SEROTONIN RECEPTOR ANTAGONISTS (5HT-2, 5HT-3) AND AGONIST (5HT-4) RESPIRATORIUS AB (SE) 2002-05-10 WO claimed
WO-2001095902-A9 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS 2002-04-25 WO claimed
WO-2001095902-A1 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS RESPIRATORIUS AB (SE) 2001-12-20 WO claimed
US-6197769-B1 SEROTONINE RECEPTORS ANTAGONIST; GASTROINTESTINAL DISORDERS, ANTIARRHYTHMIA AGENTS; INCONTINENCE AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2001-03-06 US claimed
CN-1252798-A Indazole amide compounds as 5-serotoninergic agents ANGELINI RICERCHE SPA (IT) 2000-05-10 CN claimed
EP-0975623-A2 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 2000-02-02 EP claimed
WO-1998046589-B1 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS 1999-03-04 WO claimed
WO-1998046589-A2 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 1998-10-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243181-A2 NOVEL INDAZOLE DERIVATIVE AND USE THEREOF TRIB2, YAP1, IDO2 KDM4E 2690/4885YTHDC1 2450/4885STAT3 2087/4885
US-20250092014-A1 COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE LPL, LIPA, PNLIP KDM4E 4122/4885YTHDC1 4861/4885STAT3 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.