Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | WNT3A | P56704 | 3/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82761 | 0.86 | KDM4E (0.62) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL2175299 | 0.85 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL29962256 | 0.85 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL5071439 | 0.85 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Hydrochloric Acid SCHEMBL30404733 | 0.85 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Oxalic Acid SCHEMBL6033591 | 0.82 | FLT3 (0.58) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Formic Acid SCHEMBL5987899 | 0.80 | KDM4E (0.55) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL1962245 | 0.79 | CYP1A2 (0.54) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| Trifluoroacetic Acid SCHEMBL15546473 | 0.78 | FLT3 (0.54) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL7668372 | 0.72 | KDM4E (0.66) | KDM4EYTHDC1STAT3HIF1AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573327-B | Indazole-formamide-pyridone derivative and preparation method and application thereof | 四川大学 | 2020-03-31 | — | — | CN | claimed |
| CN-107573327-B | Indazole-formamide-pyridone derivative and preparation method and application thereof | 四川大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-107573327-B | Indazole-formamide-pyridone derivative and preparation method and application thereof | 四川大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-107573327-B | Indazole-formamide-pyridone derivative and preparation method and application thereof | 四川大学 | 2020-03-31 | — | — | CN | disclosed |