Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987781 | 0.83 | MAP2K1 (0.33) | SLC22A12XDHMAPTKDM4EPOLB | |
| SCHEMBL5986530 | 0.79 | CNR2 (0.41) | MAPTKDM4EPOLBHSD17B10CA9 | |
| SCHEMBL24656012 | 0.79 | TRPA1 (0.36) | MAPTKDM4EHSD17B10PTPN1CA9 | |
| SCHEMBL5988546 | 0.75 | TRPA1 (0.32) | MAP2K1MAOATRPA1 | |
| Hydrochloric Acid SCHEMBL7789406 | 0.74 | CNR2 (0.36) | MAPTPOLBMAP2K1TSHR | |
| Hydrochloric Acid SCHEMBL5987240 | 0.74 | TRPA1 (0.31) | MAP2K1MAOATRPA1 | |
| SCHEMBL30367823 | 0.72 | PARP1 (0.43) | SLC22A12XDHMAPTKDM4EPOLB | |
| SCHEMBL25532204 | 0.72 | TRPA1 (0.32) | TRPA1 | |
| Hydrochloric Acid SCHEMBL28438885 | 0.71 | PARP1 (0.44) | SLC22A12XDHMAPTKDM4EPOLB | |
| SCHEMBL5986973 | 0.70 | P4HB (0.33) | MAPTKDM4EPOLBHSD17B10TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045545-B1 | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists | ELI LILLY AND COMPANY (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1149085-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |