Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041513 | 0.90 | ALDH1A1 (0.48) | NPC1RAB9AHPGDKDM4ENPSR1 | |
| SCHEMBL24271761 | 0.88 | ALDH1A1 (0.41) | NPC1RAB9ALCKKDM4ERXFP1 | |
| SCHEMBL5988925 | 0.88 | ALDH1A1 (0.41) | HPGDLCKKDM4EDYRK1ALMNA | |
| SCHEMBL5988791 | 0.86 | KDM4E (0.40) | LCKKDM4EDYRK1ALMNAKDM4A | |
| SCHEMBL24271886 | 0.84 | OPRM1 (0.43) | NPC1RAB9AKDM4ELMNAKDM4A | |
| SCHEMBL5987935 | 0.84 | KDM4E (0.39) | LCKKDM4EDYRK1ALMNAKDM4A | |
| SCHEMBL24271876 | 0.84 | MEN1 (0.40) | LCKKDM4EDYRK1ALMNAKDM4A | |
| SCHEMBL5989058 | 0.84 | LCK (0.37) | LCKKDM4EDYRK1ALMNAKDM4A | |
| SCHEMBL5988597 | 0.82 | KDM4E (0.41) | KDM4ENPSR1DYRK1ALMNAKDM4A | |
| SCHEMBL5988524 | 0.80 | KDM4E (0.37) | LCKKDM4ELMNAKDM4AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144902-B1 | Prodrugs of thrombin inhibitors | ABBOTT GMBH & CO. KG (DE) | 2006-12-05 | — | — | US | disclosed |
| US-6740647-B1 | AMIDINES AND HYDROXYAMIDINE DERIVATIVES | ABBOTT GMBH & CO., KG (DE) | 2004-05-25 | — | — | US | disclosed |
| CN-1355810-A | Prodrugs of thrombin inhibitors | BASF AG (DE) | 2002-06-26 | — | — | CN | disclosed |
| CN-1289341-A | Thrombin inhibitors | BASF AG (DE) | 2001-03-28 | — | — | CN | disclosed |