Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709944 | 0.88 | SLC6A4 (0.50) | L3MBTL1NPSR1HTR2CHTR2BGAA | |
| SCHEMBL5989078 | 0.83 | HTR2A (0.52) | NPSR1HTR2CHTR2BALDH1A1GAA | |
| SCHEMBL20536242 | 0.83 | LMNA (0.62) | L3MBTL1NPSR1ALDH1A1GAAKMT2A | |
| SCHEMBL5989471 | 0.82 | LMNA (0.42) | L3MBTL1NPSR1GAAKMT2AHTR2A | |
| SCHEMBL3303519 | 0.79 | ALDH1A1 (0.50) | L3MBTL1NPSR1ALDH1A1GAAKMT2A | |
| SCHEMBL15065366 | 0.78 | ALDH1A1 (0.59) | ALDH1A1GAAKMT2AHTR2ASLC6A4 | |
| SCHEMBL20535203 | 0.77 | HTR2A (0.51) | ALDH1A1HTR2ASLC6A4KCNH2TDP1 | |
| SCHEMBL5989737 | 0.77 | L3MBTL1 (0.63) | L3MBTL1NPSR1HTR2CHTR2BALDH1A1 | |
| SCHEMBL12879326 | 0.76 | L3MBTL1 (0.71) | L3MBTL1HTR2CHTR2BALDH1A1GAA | |
| SCHEMBL30191620 | 0.76 | MRGPRX4 (0.46) | L3MBTL1NPSR1ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |