Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537296 | 1.00 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Serine SCHEMBL6666261 | 0.85 | SLC7A5 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Threonine SCHEMBL5073183 | 0.85 | SLC7A5 (0.38) | GABRR1SLC7A5 | |
| Threonine SCHEMBL6856748 | 0.84 | SLC7A5 (0.36) | SLC7A5 | |
| SCHEMBL542251 | 0.83 | ALDH1A1 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15657907 | 0.83 | ALDH1A1 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL599033 | 0.82 | SLC7A5 (0.41) | SLC7A5 | |
| SCHEMBL16715223 | 0.82 | CYP1A2 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3253032 | 0.81 | TP53 (0.33) | CYP1A2LMNAKDM4EGABRR1 | |
| SCHEMBL146572 | 0.81 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240209-A1 | SYNTHESIS OF ENANTIOPURE CIS-A-IRONE FROM A RENEWABLE CARBON SOURCE | Institut National des Sciences Appliquées de Toulouse (FR) | 2024-07-18 | — | — | US | claimed |
| CN-117838627-A | Ceftiofur crystal injection and preparation method thereof | 艾美科健（中国）生物医药有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-107997979-B | Preparation method of thermosensitive liposome with whitening effect | 苏州纳康生物科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| US-20190135865-A1 | AGONIST AGENTS OF CD47 INDUCING PROGRAMMED CELL DEATH AND THEIR USE IN THE TREATMENTS OF DISEASES ASSOCIATED WITH DEFECTS IN PROGRAMMED CELL DEATH | SORBONNE UNIVERSITE (FR) | 2019-05-09 | — | — | US | claimed |
| US-20100041612-A1 | Fragments of the Glucagon-Like Peptide-1 and Uses Thereof | NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. | 2010-02-18 | — | — | US | claimed |
| US-20090202982-A1 | BLOOD-VISCOSITY REDUCING AGENT | Hitosugi, Masahito (JP) | 2009-08-13 | — | — | US | claimed |
| US-20090124555-A1 | USE OF HISTOGRANIN AND HISTOGRANIN-LIKE COMPOUNDS AS INHIBITORS OF P2X7 RECEPTOR FUNCTION AND AS ANTI-ARTHRITIC AGENTS | BERNATCHEZ-LEMAIRE IRMA | 2009-05-14 | — | — | US | claimed |
| WO-2007030706-A1 | FRAGMENTS OF THE GLUCAGON-LIKE PEPTIDE-I AND USES THEREOF | NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. (US) | 2007-03-15 | — | — | WO | claimed |
| EP-0800385-B1 | ORAL SUSTAINED-RELEASE PREPARATION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-12-20 | — | — | EP | claimed |
| EP-1027031-A2 | STABILIZED ALUMINIUM ZIRCONIUM ANTIPERSPIRANT COMPOSITIONS | Colgate-Palmolive Company (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1999021528-A2 | STABILIZED ALUMINIUM ZIRCONIUM ANTIPERSPIRANT COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 1999-05-06 | — | — | WO | claimed |
| EP-0832110-A1 | ANTIVIRAL PEPTOID COMPOUNDS | Novartis AG (CH) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040759-A1 | ANTIVIRAL PEPTOID COMPOUNDS | NOVARTIS AG (CH) | 1996-12-19 | — | — | WO | claimed |
| EP-0506628-B1 | Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances | SIGMA TAU IND FARMACEUTI (IT) | 1996-09-18 | — | — | EP | claimed |
| US-5061806-A | Phosphinic acid derivatives | MERCK & CO., INC. (US) | 1991-10-29 | — | — | US | claimed |
| EP-0118280-B1 | ENZYME INHIBITION | Aktiebolaget Hässle (SE) | 1989-07-12 | — | — | EP | claimed |
| WO-1988006034-A1 | DERMAL COSMETIC COMPOSITION AND APPLICATIONS THEREFOR | FIASCHETTI MARY GEMMA (US) | 1988-08-25 | — | — | WO | claimed |
| WO-1984003507-A1 | ENZYME INHIBITION | FERRING AB (SE) | 1984-09-13 | — | — | WO | claimed |
| EP-0118280-A1 | Enzyme inhibition | Aktiebolaget Hässle (SE) | 1984-09-12 | — | — | EP | claimed |
| US-4238306-A | Electrodialysis process for the separation of non-essential amino acids from derivatives thereof | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1980-12-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135865-A1 | AGONIST AGENTS OF CD47 INDUCING PROGRAMMED CELL DEATH AND THEIR USE IN THE TREATMENTS OF DISEASES ASSOCIATED WITH DEFECTS IN PROGRAMMED CELL DEATH | CD47, BID, CD274 | GRIN2D 4612/4885GRIN3B 3475/4885GRIN1 3370/4885 |
| US-20090124555-A1 | USE OF HISTOGRANIN AND HISTOGRANIN-LIKE COMPOUNDS AS INHIBITORS OF P2X7 RECEPTOR FUNCTION AND AS ANTI-ARTHRITIC AGENTS | P2RX5, P2RX3, P2RX2 | GRIN2D 954/4885GRIN3B 130/4885GRIN1 277/4885 |
| US-20100041612-A1 | Fragments of the Glucagon-Like Peptide-1 and Uses Thereof | GLP1R, IAPP, GIPR | GRIN2D 4321/4885GRIN3B 2604/4885GRIN1 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.