Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994455 | 0.92 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3973235 | 0.89 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3067821 | 0.85 | S1PR4 (0.54) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL5989232 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL3064859 | 0.81 | PPARD (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6624465 | 0.81 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3976902 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3065371 | 0.79 | F2R (0.59) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3065363 | 0.79 | SMO (0.50) | ALDH1A1MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL3044614 | 0.79 | SMO (0.50) | MEN1KMT2ACYP1A2RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673360-A1 | FURAN DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LIMITED (GB) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005037812-A1 | FURAN DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |