Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.55 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.55 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818048 | 0.96 | S1PR1 (0.56) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL4817037 | 0.85 | S1PR1 (0.71) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL27441500 | 0.84 | RIPK1 (0.47) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL14268150 | 0.84 | S1PR1 (0.70) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL904016 | 0.80 | S1PR1 (0.58) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL8498023 | 0.78 | TNNC1 (0.57) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7615664 | 0.78 | S1PR1 (0.63) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7615930 | 0.78 | S1PR1 (0.63) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Hydrochloric Acid SCHEMBL8497906 | 0.78 | S1PR1 (0.59) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL3080036 | 0.78 | TRPA1 (0.51) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39072-E1 | 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-18 | — | — | US | claimed |
| EP-1002792-B1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-07-14 | — | — | EP | claimed |
| US-6214873-B1 | PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY | WELFIDE CORPORATION (JP) | 2001-04-10 | — | — | US | claimed |
| EP-1002792-A1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-24 | — | — | EP | claimed |
| CN-1290819-C | 2-aminopropane-1,3-glycol compound, its use as medicine and its synthetic intermediate | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2006-12-20 | — | — | CN | disclosed |
| US-RE39072-E1 | 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-18 | — | — | US | disclosed |
| US-RE39072-E1 | 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-18 | — | — | US | disclosed |
| EP-1002792-B1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1002792-B1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-07-14 | — | — | EP | disclosed |
| CN-1480450-A | 2-aminopropane-1,3-glycol compound, its use as medicine and its synthetic intermediate | ������ҩ��ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1137086-C | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | ������ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| EP-1319651-A2 | 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor | Mitsubishi Pharma Corporation (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-1002792-A4 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | MITSUBISHI PHARMA CORP (JP) | 2002-03-20 | — | — | EP | disclosed |
| US-6214873-B1 | PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY | WELFIDE CORPORATION (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6214873-B1 | PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY | WELFIDE CORPORATION (JP) | 2001-04-10 | — | — | US | disclosed |
| CN-1259117-A | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-07-05 | — | — | CN | disclosed |
| EP-1002792-A1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-1002792-A1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |
| WO-1998045249-A1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-15 | — | — | WO | disclosed |