Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989750 | 0.88 | TRPA1 (0.38) | TRPA1CNR1CNR2TMIGD3ADORA2A | |
| SCHEMBL23991290 | 0.81 | BACE1 (0.58) | CNR1CNR2TMIGD3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL23629396 | 0.80 | BACE1 (0.56) | CNR1CNR2MAPTKDM4ETP53 | |
| SCHEMBL29763176 | 0.78 | TRPA1 (0.70) | TRPA1CNR1CNR2MAPTKDM4E | |
| SCHEMBL8047684 | 0.78 | TRPA1 (0.70) | TRPA1CNR1CNR2MAPTKDM4E | |
| SCHEMBL14027112 | 0.78 | RPS6KB2 (0.53) | TMIGD3ADORA2AADORA1MAPTKDM4E | |
| SCHEMBL5990688 | 0.78 | ERN1 (0.47) | MAPTKDM4ETP53SMN1; SMN2MEN1 | |
| SCHEMBL4124686 | 0.77 | CSNK2A1 (0.42) | ADORA2AADORA1MAPTKDM4ETP53 | |
| SCHEMBL27968468 | 0.74 | MAPT (0.41) | ADORA2AADORA1MAPTKDM4ETP53 | |
| SCHEMBL13996579 | 0.74 | TRPA1 (0.46) | TRPA1CNR1CNR2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |