SCHEMBL4124686

SCHEMBL4124686

CCc1ccc(-c2cccs2)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 3/20 0.42
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A3 Q8NEV1 1/20 0.42
LTA4H P09960 2/20 0.41
MAPT P10636 5/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9335164 0.77 LMNA (0.50) MAPTKDM4ETP53L3MBTL1SMN1; SMN2
SCHEMBL5990907 0.77 TRPA1 (0.48) LTA4HMAPTKDM4ETP53THRB
SCHEMBL5990688 0.74 ERN1 (0.47) MAPTKDM4ETP53SMN1; SMN2ALDH1A1
SCHEMBL4962984 0.74 CYP3A4 (0.43) MAPTKDM4ETP53L3MBTL1SMN1; SMN2
SCHEMBL27282332 0.73 LTA4H (0.40) LTA4HMAPTKDM4ETP53L3MBTL1
SCHEMBL11111178 0.72 AHR (0.46) LTA4HMAPTKDM4EL3MBTL1SMN1; SMN2
SCHEMBL17859650 0.72 CSNK2A1 (0.68) CSNK2A1CSNK2A2CSNK2BCSNK2A3MAPT
SCHEMBL404521 0.71 LTA4H (0.68) LTA4HMAPTKDM4ETP53THRB
SCHEMBL158066 0.70 PRMT6 (0.68) LTA4HMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL1310734 0.70 ALDH1A1 (0.61) LTA4HMAPTKDM4EL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100585902-C Organic semiconductor material and organic field effect transistor MITSUBISHI CHEM CORP 2010-01-27 CN disclosed
US-20090159876-A1 ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC FIELD EFFECT TRANSISTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-06-25 US disclosed
CN-101268566-A Organic semiconductor material and organic field effect transistor MITSUBISHI CHEM CORP (JP) 2008-09-17 CN disclosed
EP-1947706-A1 ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC FIELD EFFECT TRANSISTOR Mitsubishi Chemical Corporation (JP) 2008-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090159876-A1 ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC FIELD EFFECT TRANSISTOR H1-4, OR10J3, EPCAM CSNK2A1 2531/4885CSNK2A2 2352/4885CSNK2B 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.