SCHEMBL8047684

SCHEMBL8047684

CCc1ccc(O)c(-c2cc(CC)ccc2O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.70
CNR1 P21554 2/20 0.68
CNR2 P34972 2/20 0.68
ALDH1A1 P00352 4/20 0.54
MAPT P10636 4/20 0.54
KDM4E B2RXH2 3/20 0.54
GAA P10253 3/20 0.54
GABRA1 P14867 2/20 0.54
GABRB2 P47870 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH2 P05091 1/20 0.54
AKR1B1 P15121 1/20 0.54
HPGD P15428 1/20 0.54
PPARG P37231 1/20 0.54
PPARD Q03181 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ALOX5 P09917 1/20 0.47
POLB P06746 1/20 0.47
NPC1 O15118 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763176 1.00 TRPA1 (0.70) TRPA1CNR1CNR2ALDH1A1MAPT
Sulfur Dioxide SCHEMBL20526202 0.91 TRPA1 (0.59) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL25383045 0.89 CNR1 (0.88) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL23986122 0.89 TRPA1 (0.57) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL4288864 0.89 TRPA1 (0.57) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL12327572 0.84 TRPA1 (0.52) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL15026755 0.84 MAPT (0.53) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL20153052 0.84 GABRA1 (0.82) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL4286160 0.83 BACE1 (0.64) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL7083937 0.83 TRPA1 (0.55) TRPA1CNR1CNR2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321958-A1 LIQUID CRYSTAL POLYMER FILM, POLYMER FILM, AND LAMINATE FUJIFILM CORPORATION (JP) 2023-10-12 US disclosed
US-11725093-B2 Bioderived heat transfer fluids and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2023-08-15 US disclosed
US-20220211727-A1 Mito-Magnolol Compounds and Methods of Synthesis and Use Thereof AIX-MARSEILLE UNIVERSITE (FR) 2022-07-07 US disclosed
US-20210356879-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE, AND PLANOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2021-11-18 US disclosed
CN-104053663-B Process for purifying organodiphosphite compounds 巴斯夫欧洲公司 2017-07-04 CN disclosed
US-9315435-B2 Method for producing hydroxyphenylcyclohexanol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
EP-1948684-B1 PRODUCTION OF RECOMBINANT COLLAGEN LIKE PROTEINS AMSILK GMBH (DE) 2016-01-27 EP disclosed
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-21 US disclosed
EP-2842930-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
US-6031061-A Bis (triaklyltrimellitic anhydride) derivative and polyesterimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND HSD11B2, CYP21A2, CYP11B2 TRPA1 2672/4885CNR1 292/4885CNR2 176/4885
US-20220211727-A1 Mito-Magnolol Compounds and Methods of Synthesis and Use Thereof CYP11B1, MFN2, CYP11B2 TRPA1 3369/4885CNR1 2766/4885CNR2 2796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.