SCHEMBL5991335

SCHEMBL5991335

CSC1=NCCCS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13508174 0.82
Hydrochloric Acid SCHEMBL10840793 0.82
Iodide SCHEMBL11169882 0.82
SCHEMBL6032777 0.75
SCHEMBL762220 0.69
SCHEMBL6033517 0.67 NOS3 (0.39)
SCHEMBL6033067 0.66 ALDH1A1 (0.41)
SCHEMBL6033461 0.65 MAPT (0.39)
SCHEMBL8142930 0.65
SCHEMBL12217234 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084137-B2 Thiazines and thiazoles as agents for protecting materials BAYER AKTIENGESELLSCHAFT (DE) 2006-08-01 US claimed
US-20040204405-A1 Thiazines and thiazoles as agents for protecting materials LANXESS DEUTSCHLAND GMBH (DE) 2004-10-14 US claimed
EP-1437940-A1 THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS Bayer Chemicals AG (DE) 2004-07-21 EP claimed
US-20030129081-A1 Thiazines and thiazoles as agents for protecting materials BAYER AKTIENGESELLSCHAFT (DE) 2003-07-10 US claimed
WO-2003001913-A1 THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS BAYER CHEMICALS AG (DE) 2003-01-09 WO claimed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
WO-2024249291-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF CASMA THERAPEUTICS, INC. (US) 2024-12-05 WO disclosed
US-20230365556-A1 N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. (US) 2023-11-16 US disclosed
US-20230365556-A1 N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. (US) 2023-11-16 US disclosed
US-11673887-B2 N-acyl amino acid compounds and methods of use PLIANT THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
US-11673887-B2 N-acyl amino acid compounds and methods of use PLIANT THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
US-20210024516-A1 N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. 2021-01-28 US disclosed
US-4020061-A 3-Oxomethyl-2-(1-nitro-2-oxoethylidene)-tetrahydro-2H-1,3-thiazines SHELL OIL COMPANY (US) 1977-04-26 US disclosed
US-4015001-A Control of insects by nitro(tetrahydro-2H-1,3-thiazin-2-ylidene)methyl aldehydes and ketones SHELL OIL COMPANY (US) 1977-03-29 US disclosed
US-4013766-A N-(NITRO(TETRAHYDRO-2H-1,3-THIAZIN-2-YLIDENE)ACETYL)BENZAMIDES SHELL OIL COMPANY (US) 1977-03-22 US disclosed
US-3993648-A Tetrahydro-2-(nitromethylene)-2H-1,3-thiazines SHELL OIL COMPANY (US) 1976-11-23 US disclosed
US-3962233-A INSECTICIDES SHELL OIL COMPANY (US) 1976-06-08 US disclosed
US-3962225-A NITRO(TETRAHYDRO-2H-1,3-THIAZIN-2-YLIDENE)METHYL ALDEHYDES AND KETONES SHELL OIL COMPANY (US) 1976-06-08 US disclosed
US-3962234-A INSECTICIDES SHELL OIL COMPANY (US) 1976-06-08 US disclosed
US-3933809-A 2-(Dihalonitromethyl)-5,6-dihydro-4H-1,3-thiazines SHELL OIL COMPANY (US) 1976-01-20 US disclosed