Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033049 | 0.83 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL6033404 | 0.79 | ALDH1A1 (0.41) | MAPTSMN1; SMN2ALDH1A1ALOX15LMNA | |
| SCHEMBL6032247 | 0.79 | NOS3 (0.35) | MAPTALDH1A1TSHRLMNARAB9A | |
| SCHEMBL6032664 | 0.79 | TSHR (0.43) | MAPTTSHRHSD17B10LMNARAB9A | |
| SCHEMBL6033318 | 0.79 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL6033067 | 0.79 | ALDH1A1 (0.41) | MAPTSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL6033133 | 0.79 | PTGIR (0.43) | MAPTSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL6032640 | 0.73 | GFER (0.52) | MAPTSMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL6033077 | 0.72 | HAO1 (0.40) | MAPTLMNATDP1RAB9ANOS3 | |
| SCHEMBL5701837 | 0.71 | ALDH1A1 (0.65) | MAPTSMN1; SMN2ALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | claimed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | claimed |
| EP-1437940-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | Bayer Chemicals AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | claimed |
| WO-2003001913-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | BAYER CHEMICALS AG (DE) | 2003-01-09 | — | — | WO | claimed |
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | disclosed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | disclosed |
| EP-1437940-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | Bayer Chemicals AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | disclosed |
| WO-2003001913-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | BAYER CHEMICALS AG (DE) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | MAPT 2345/4885SMN1; SMN2 1705/4885ALDH1A1 40/4885 |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | MAPT 2345/4885SMN1; SMN2 1705/4885ALDH1A1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.